Reduction of Immunosuppression as Initial Therapy for Posttransplantation Lymphoproliferative Disorder★
نویسندگان
چکیده
منابع مشابه
Primary intraocular posttransplantation lymphoproliferative disorder.
We report a case of posttransplantation lymphoproliferative disorder manifesting as an isolated, unilateral iris tumor. A 2-year-old boy who had undergone liver transplantation for biliary atresia at age 4 months was seen with a 2-month history of an enlarging iris nodule. Histopathologic examination of the iris lesion demonstrated a mixed population of lymphoid cells. To our knowledge, this is...
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Posttransplantation lymphoproliferative disorders (PTLD) are lymphoid proliferations or lymphomas that develop as a result of immunosuppression in recipients of solid organs and bone marrow allografts. The disorder is seen in 1-2% of renal transplant recipients with a variable time period of presentation and is usually seen within the first year following transplantation. We report a case of B-...
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Posttransplantation lymphoproliferative disorder (PTLD) is a serious complication following solid organ transplantation. Most of PTLD is related to an interaction of Epstein-Barr virus (EBV) infection and immune suppression. PTLD occurs most common after intestine transplantation and the least common after renal transplantation. PTLD can involve any organs. Abdominal organs are frequently invol...
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Posttransplantation lymphoproliferative disorder (PTLD) is a recognized and extremely morbid complication of solid organ transplantation, but central nervous system involvement, particularly in isolation, is rare. There are no standardized treatment strategies for PTLD, though commonly used strategies include reduction of immunosuppression, chemotherapy, rituximab, radiation, and surgery. We pr...
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Posttransplantation lymphoproliferative disorders (PTLDs) represent a serious complication of solid organ transplantation. This study assessed the molecular histogenesis of 52 B-cell monoclonal PTLDs, including 12 polymorphic PTLDs (P-PTLDs), 36 diffuse large B-cell lymphomas (DLBCLs), and 4 Burkitt/Burkitt-like lymphomas (BL/BLLs). Somatic hypermutation (SHM) of immunoglobulin variable (IgV) g...
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ژورنال
عنوان ژورنال: American Journal of Transplantation
سال: 2011
ISSN: 1600-6135
DOI: 10.1111/j.1600-6143.2010.03387.x